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KMID : 0882420120830050641
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Korean Journal of Medicine
2012 Volume.83 No. 5 p.641 ~ p.646
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Primary Hyperparathyroidism with Ectopic Parathyroid Adenoma Detected by Both 99mTc-MIBI SPECT and Contrast-Enhanced Neck CT
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Lim Hye-Jin
Shin Dong-Geum
Kim Jun-Bong
Kim Jin-Taek
Kim Hyo-Jeong
Park Man-Sil
Lee Ho-Jung
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Abstract
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An ectopic parathyroid gland is a major cause of persistent and recurrent hyperparathyroidism. Surgical success depends on accurate preoperative localization of the parathyroid adenoma. We herein report the case of a 52-year-old male patient who suffered from primary hyperparathyroidism for several years. He initially presented with urinary frequency, hypercalcemia, and a ureter stone. Ultrasonography and a 99mTc-sestamibi scan were performed, but failed to localize the parathyroid lesion. Four years later, the patient revisited our hospital, complaining of general weakness, headache, dyspepsia, and recurrent urinary symptoms secondary to persistent primary hyperparathyroidism. In addition, renal function was decreased and severe osteoporosis was found. We performed a 99mTc-sestamibi scan with single photon emission computed tomography (99mTc-MIBI SPECT) and contrastenhanced neck CT, and detected an ectopic parathyroid adenoma in the upper anterior mediastinum. In conclusion, the combination of both 99mTc-MIBI SPECT and neck CT could permit better preoperative parathyroid localization, especially for mediastinal adenomas.
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KEYWORD
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Hyperparathyroidism, primary, Parathyroid neoplasms, Technetium Tc 99m-sestamibi, Tomography, emission-computed, single-photon
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